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Vittorio Gentile Selected Research

Transglutaminases

1/2014Possible physiopathological effects of the transglutaminase activity on the molecular mechanisms responsible for human neurodegenerative diseases.
1/2014Possible physiopathological roles of the transglutaminase activity in the etiopathogenesis of human neurodegenerative diseases.
12/2013Transglutaminase activity as a possible therapeutical target in neurodegenerative diseases.
8/2013Transglutaminase inhibition as a possible therapeutical approach to protect cells from death in neurodegenerative diseases.
1/2013Possible involvement of transglutaminase-catalyzed reactions in the physiopathology of neurodegenerative diseases.
2/2011Possible role of the transglutaminases in the pathogenesis of Alzheimer's disease and other neurodegenerative diseases.
11/2010Transglutaminases as possible therapeutic targets in neurodegenerative diseases.
3/2008Role of transglutaminase-catalyzed reactions in the post-translational modifications of proteins responsible for immunological disorders.
1/2006Molecular mechanisms responsible for the involvement of tissue transglutaminase in human diseases: Celiac Disease.

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Vittorio Gentile Research Topics

Disease

13Neurodegenerative Diseases (Neurodegenerative Disease)
01/2014 - 01/2002
10Huntington Disease (Huntington's Disease)
01/2014 - 01/2002
9Alzheimer Disease (Alzheimer's Disease)
01/2014 - 04/2004
9Paralysis (Palsy)
01/2014 - 04/2004
9Parkinson Disease (Parkinson's Disease)
01/2014 - 04/2004
6Celiac Disease (Celiac Sprue)
01/2014 - 01/2006
4Pathologic Processes
01/2014 - 05/2010
1Autoimmune Diseases (Autoimmune Disease)
01/2014
1Neuroblastoma
01/2013
1Nervous System Diseases (Neurological Disorders)
11/2012
1Abetalipoproteinemia (Bassen Kornzweig Syndrome)
10/2002

Drug/Important Bio-Agent (IBA)

13Proteins (Proteins, Gene)FDA Link
01/2014 - 01/2002
9polyglutamineIBA
01/2014 - 01/2006
9TransglutaminasesIBA
01/2014 - 01/2006
5EnzymesIBA
08/2013 - 03/2008
3Protein Glutamine gamma Glutamyltransferase 2IBA
08/2013 - 01/2006
2Therapeutic UsesIBA
01/2013 - 02/2011
1Protein Isoforms (Isoforms)IBA
11/2012
1CystamineIBA
04/2004
1Cysteamine (Mercaptamine)FDA Link
04/2004
1AntioxidantsIBA
04/2004
1Creatine Kinase (Creatine Phosphokinase)IBA
10/2002
1Protein AggregatesIBA
01/2002